CAPNL1 antibody (Middle Region)

Catalog No. ABIN5515582

Product Details anti-CAPNL1 Antibody

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PATFWVNPQF KIRLDETDDP DDYGDRESGC SFVLALMQKH RRRERRFGRD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CAPN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Alternative Name: CAPN1 (CAPNL1 Products)

Synonyms: CANP antibody, CANP1 antibody, CANPL1 antibody, muCANP antibody, muCL antibody, Capa-1 antibody, Capa1 antibody, mu-calpin antibody, si:ch211-203k12.4 antibody, si:dkeyp-101g1.3 antibody, calpain antibody, calpain 1 antibody, calpain 1, (mu/I) large subunit antibody, calpain 1, (mu/I) large subunit b antibody, calpain 11 antibody, CAPN1 antibody, Capn1 antibody, capn1 antibody, capn1b antibody, CAPN11 antibody

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Alias Symbols: CANP, muCL, CANP1, CANPL1, muCANP

Protein Size: 714

Gene ID: 823

NCBI Accession: NM_001198868, NP_001185797

UniProt: P07384

Pathways: Apoptosis