Relaxin 2 antibody (Middle Region)

Catalog No. ABIN5515612

Product Details anti-Relaxin 2 Antibody

Target: Relaxin 2 (RLN2)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FKKLIRNRQS EAADSSPSEL KYLGLDTHSR KKRQLYSALA NKCCHVGCTK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RLN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Relaxin 2

Target: Relaxin 2 (RLN2)

Alternative Name: RLN2 (RLN2 Products)

Synonyms: H2 antibody, H2-RLX antibody, RLXH2 antibody, bA12D24.1.1 antibody, bA12D24.1.2 antibody, RFLX antibody, rln2 antibody, rln3c antibody, rlx3c antibody, si:rp71-39b20.5 antibody, relaxin 2 antibody, insulin-like 3 (Leydig cell) antibody, RLN2 antibody, insl3 antibody

Background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the protein encoded by this gene consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. Alternative splicing of this gene results in multiple transcript variants.

Alias Symbols: H2, RLXH2, H2-RLX, bA12D24.1.1, bA12D24.1.2

Protein Size: 167

Gene ID: 6019

NCBI Accession: NM_005059, NP_005050

UniProt: P04090

Pathways: Hormone Activity