ESCO2 antibody (Middle Region)

Catalog No. ABIN5515715

Product Details anti-ESCO2 Antibody

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESCO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IYKPIVEKEN NCHSAENNSN APRVLSQKIK PQVTLQGGAA FFVRKKSSLR

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ESCO2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ESCO2

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Alternative Name: ESCO2 (ESCO2 Products)

Synonyms: rbs antibody, efo2 antibody, MGC115718 antibody, si:dkey-217m5.6 antibody, zgc:111795 antibody, 2410004I17Rik antibody, D030072L07Rik antibody, EFO2 antibody, RBS antibody, establishment of sister chromatid cohesion N-acetyltransferase 2 antibody, establishment of sister chromatid cohesion N-acetyltransferase 2 S homeolog antibody, ESCO2 antibody, Esco2 antibody, esco2.S antibody, esco2 antibody

Background: This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome.

Alias Symbols: RBS, EFO2, 2410004I17Rik,

Protein Interaction Partner: CBX8, UBC, RCOR1, KDM1A, EHMT2, SETDB1, HDAC4, SUV39H1, HDAC2, HDAC1, PHF21A,

Protein Size: 601

Gene ID: 157570

NCBI Accession: NM_001017420, NP_001017420

UniProt: Q56NI9

Pathways: Positive Regulation of Endopeptidase Activity