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GIT1 antibody (Middle Region)
GIT1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GIT1 Antibody
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Target
See all GIT1 Antibodies
GIT1
Binding Specificity
All epitopes for GIT1 antibodies
Middle Region
Reactivity
All reactivities for GIT1 antibodies
Human
Host
All hosts for GIT1 antibodies
Rabbit
Clonality
All clonalities for GIT1 antibodies
Polyclonal
Conjugate
All conjugates for GIT1 antibodies
This GIT1 antibody is un-conjugated
Application
All applications for GIT1 antibodies
Western Blotting (WB)
Sequence
RKGVSASAVP FTPSSPLLSC SQEGSRHTSK LSRHGSGADS DYENTQSGDP
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GIT1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GIT1
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Target
GIT1
Alternative Name
GIT1 (GIT1 Products )
Synonyms
Cat-1 antibody, p95Cat antibody, GIT ArfGAP 1 antibody, G protein-coupled receptor kinase interacting ArfGAP 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, Git1 antibody
Background
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis, the function may involve SDCCAG3 and PTPN13. Protein Size: 761
Gene ID
28964
NCBI Accession
NM_001085454 , NP_001078923
UniProt
Q9Y2X7
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