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GIT1 antibody (Middle Region)

GIT1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5515733
  • Target See all GIT1 Antibodies
    GIT1
    Binding Specificity
    • 15
    • 15
    • 15
    • 14
    • 12
    • 8
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 72
    • 43
    • 34
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 100
    • 14
    Rabbit
    Clonality
    • 92
    • 22
    Polyclonal
    Conjugate
    • 37
    • 9
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GIT1 antibody is un-conjugated
    Application
    • 86
    • 39
    • 39
    • 37
    • 19
    • 17
    • 17
    • 16
    • 13
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    RKGVSASAVP FTPSSPLLSC SQEGSRHTSK LSRHGSGADS DYENTQSGDP
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GIT1
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    Discover our top product GIT1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GIT1
    Alternative Name
    GIT1 (GIT1 Products)
    Synonyms
    Cat-1 antibody, p95Cat antibody, GIT ArfGAP 1 antibody, G protein-coupled receptor kinase interacting ArfGAP 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, Git1 antibody
    Background
    GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis, the function may involve SDCCAG3 and PTPN13.

    Protein Size: 761
    Gene ID
    28964
    NCBI Accession
    NM_001085454, NP_001078923
    UniProt
    Q9Y2X7
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