ALAD antibody (Middle Region)
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- Target See all ALAD Antibodies
- ALAD (Aminolevulinate Dehydratase (ALAD))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ALAD antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ALAD
- Top Product
- Discover our top product ALAD Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ALAD (Aminolevulinate Dehydratase (ALAD))
- Alternative Name
- ALAD (ALAD Products)
- Synonyms
- DDBDRAFT_0190269 antibody, DDBDRAFT_0231415 antibody, DDB_0190269 antibody, DDB_0231415 antibody, ALAD antibody, ncf antibody, ALADH antibody, PBGS antibody, ALADR antibody, aminolevulinatedelta-dehydratase antibody, zgc:110219 antibody, Lv antibody, delta-aminolevulinate dehydratase antibody, aminolevulinate dehydratase antibody, delta-aminolevulinic acid dehydratase antibody, Delta-aminolevulinic acid dehydratase antibody, aminolevulinate dehydratase L homeolog antibody, aminolevulinate, delta-, dehydratase antibody, hemB antibody, ALAD antibody, PBGS antibody, STY0404 antibody, SAS1597 antibody, SACI_RS03725 antibody, PAAG_00299 antibody, VDBG_00315 antibody, HPPC_00830 antibody, MGYG_01952 antibody, hem2 antibody, alad.L antibody, Alad antibody, alad antibody
- Background
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: PBGS, ALADH,
Protein Size: 330 - Gene ID
- 210
- NCBI Accession
- NM_000031, NP_000022
- UniProt
- P13716
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