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IRAK4 antibody (N-Term)
IRAK4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IRAK4 Antibody
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Target
See all IRAK4 Antibodies
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Binding Specificity
All epitopes for IRAK4 antibodies
N-Term
Reactivity
All reactivities for IRAK4 antibodies
Human
Host
All hosts for IRAK4 antibodies
Rabbit
Clonality
All clonalities for IRAK4 antibodies
Polyclonal
Conjugate
All conjugates for IRAK4 antibodies
This IRAK4 antibody is un-conjugated
Application
All applications for IRAK4 antibodies
Western Blotting (WB)
Sequence
VQQKQMPFCD KDRTLMTPVQ NLEQSYMPPD SSSPENKSLE VSDTRFHSFS
Characteristics
This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human IRAK4
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for IRAK4
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Target
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Alternative Name
IRAK4 (IRAK4 Products )
Synonyms
zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. Alias Symbols: IRAK4 Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC, Protein Size: 460
Gene ID
51135
UniProt
Q9NWZ3
Pathways
NF-kappaB Signaling , TLR Signaling , Activation of Innate immune Response , Toll-Like Receptors Cascades
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