MKNK1 antibody (N-Term)

Catalog No. ABIN5516094

Product Details anti-MKNK1 Antibody

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EPLPIADGDR RRKKKRRGRA TDSLPGKFED MYKLTSELLG EGAYAKVQGA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MKNK1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MKNK1 (MKNK1 Products)

Synonyms: MNK1 antibody, MKNK1 antibody, zgc:171912 antibody, 2410048M24Rik antibody, Mnk1 antibody, MAPK signal-integrating kinase 1 antibody, mknk1 antibody, mnk1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase-interacting serine/threonine kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 S homeolog antibody, MKNK1 antibody, mknk1 antibody, Mknk1 antibody, mknk1.S antibody

Background: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alias Symbols: MNK1

Protein Size: 465

Gene ID: 8569

NCBI Accession: NM_001135553, NP_001129025

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor