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SEMA4D/CD100 antibody (Middle Region)
SEMA4D
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SEMA4D/CD100 Antibody
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Target
See all SEMA4D/CD100 (SEMA4D) Antibodies
SEMA4D/CD100 (SEMA4D)
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Binding Specificity
All epitopes for SEMA4D/CD100 antibodies
Middle Region
Reactivity
All reactivities for SEMA4D/CD100 antibodies
Human
Host
All hosts for SEMA4D/CD100 antibodies
Rabbit
Clonality
All clonalities for SEMA4D/CD100 antibodies
Polyclonal
Conjugate
All conjugates for SEMA4D/CD100 antibodies
This SEMA4D/CD100 antibody is un-conjugated
Application
All applications for SEMA4D/CD100 antibodies
Western Blotting (WB)
Sequence
ISRNSSHSPL RTEYAIPWLN EPSFVFADVI RKSPDSPDGE DDRVYFFFTE
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SEMA4D
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SEMA4D/CD100
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Target
SEMA4D/CD100 (SEMA4D)
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Alternative Name
SEMA4D (SEMA4D Products )
Synonyms
C9orf164 antibody, CD100 antibody, M-sema-G antibody, SEMAJ antibody, coll-4 antibody, Semacl2 antibody, Semaj antibody, Semcl2 antibody, COLL-4 antibody, semaphorin 4D antibody, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antibody, Sema4d antibody, SEMA4D antibody
Background
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system, induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. Alias Symbols: CD100, SEMAJ, coll-4, C9orf164, M-sema-G Protein Size: 862
Gene ID
10507
NCBI Accession
NM_001142287 , NP_001135759
UniProt
Q92854
Pathways
Regulation of Cell Size
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