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CXCR1 antibody (Middle Region)
CXCR1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CXCR1 Antibody
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Target
See all CXCR1 Antibodies
CXCR1
(Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
Binding Specificity
All epitopes for CXCR1 antibodies
Middle Region
Reactivity
All reactivities for CXCR1 antibodies
Human
Host
All hosts for CXCR1 antibodies
Rabbit
Clonality
All clonalities for CXCR1 antibodies
Polyclonal
Conjugate
All conjugates for CXCR1 antibodies
This CXCR1 antibody is un-conjugated
Application
All applications for CXCR1 antibodies
Western Blotting (WB)
Sequence
ILLLACISVD RYLAIVHATR TLTQKRHLVK FVCLGCWGLS MNLSLPFFLF
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CXCR1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CXCR1
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Target
CXCR1
(Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
Alternative Name
CXCR1 (CXCR1 Products )
Synonyms
C-C antibody, C-C-CKR-1 antibody, CD128 antibody, CD181 antibody, CDw128a antibody, CKR-1 antibody, CMKAR1 antibody, IL8R1 antibody, IL8RA antibody, IL8RBA antibody, Il8ra antibody, CXCR-1 antibody, IL-8RA antibody, CXCR2 antibody, IL8RB antibody, cxcr1 antibody, cxcr2 antibody, C-X-C motif chemokine receptor 1 antibody, chemokine (C-X-C motif) receptor 1 antibody, C-X-C chemokine receptor type 1 antibody, C-X-C motif chemokine receptor 1 S homeolog antibody, CXCR1 antibody, Cxcr1 antibody, LOC100461947 antibody, cxcr1.S antibody
Background
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alias Symbols: C-C, CD128, CD181, CKR-1, IL8R1, IL8RA, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1 Protein Size: 200
Gene ID
3577
NCBI Accession
NP_000625
UniProt
C9JW47
Pathways
cAMP Metabolic Process
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