GRIA4 antibody (Middle Region)

Catalog No. ABIN5516759

Product Details anti-GRIA4 Antibody

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIA4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL

Characteristics: This is a rabbit polyclonal antibody against GRIA4. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GRIA4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRIA4

Target: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Alternative Name: GRIA4 (GRIA4 Products)

Synonyms: GLUR4 antibody, GLUR4C antibody, GLURD antibody, GluA4 antibody, GluR4 antibody, GluR4d antibody, GLUR4/D antibody, glur4 antibody, GluR-D antibody, Glur-4 antibody, Glur4 antibody, Gluralpha4 antibody, spkw1 antibody, DKFZp459P0616 antibody, glur4a antibody, gria4 antibody, iGluR4 antibody, ZfGluR4b antibody, fj46g06 antibody, glur4b antibody, wu:fj46g06 antibody, glutamate ionotropic receptor AMPA type subunit 4 antibody, glutamate receptor, ionotropic, AMPA 4 antibody, glutamate receptor, ionotropic, AMPA4 (alpha 4) antibody, glutamate receptor, ionotropic, AMPA 4a antibody, glutamate receptor, ionotropic, AMPA 4b antibody, GRIA4 antibody, gria4 antibody, Gria4 antibody, gria4a antibody, gria4b antibody

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

Alias Symbols: GRIA4, GLUR4,

Protein Size: 433

Gene ID: 2893

Pathways: PI3K-Akt Signaling