SGCA antibody (Middle Region)

Catalog No. ABIN5516845

Product Details anti-SGCA Antibody

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QVIEVTAYNR DSFDTTRQRL VLEIGDPEGP LLPYQAEFLV RSHDAEEVLP

Characteristics: This is a rabbit polyclonal antibody against SGCA. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SGCA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGCA

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Alternative Name: SGCA (SGCA Products)

Synonyms: Sgca antibody, 50-DAG antibody, A2 antibody, ADL antibody, DAG2 antibody, DMDA2 antibody, LGMD2D antibody, SCARMD1 antibody, adhalin antibody, 50DAG antibody, Asg antibody, sarcoglycan alpha antibody, sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody, sarcoglycan, alpha antibody, SGCA antibody, Sgca antibody

Background: This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: SGCA, ADL, DAG2,

Protein Size: 263

Gene ID: 6442

NCBI Accession: NP_001129169