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MAML1 antibody (Middle Region)
MAML1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAML1 Antibody
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Target
See all MAML1 Antibodies
MAML1
(Mastermind-Like 1 (MAML1))
Binding Specificity
All epitopes for MAML1 antibodies
Middle Region
Reactivity
All reactivities for MAML1 antibodies
Human
Host
All hosts for MAML1 antibodies
Rabbit
Clonality
All clonalities for MAML1 antibodies
Polyclonal
Conjugate
All conjugates for MAML1 antibodies
This MAML1 antibody is un-conjugated
Application
All applications for MAML1 antibodies
Western Blotting (WB)
Sequence
VNKSSPRPGG PYLQPSHVNL LSHQPPSNLN QNSANNQGSV LDYGNTKPLS
Characteristics
This is a rabbit polyclonal antibody against MAML1. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human MAML1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MAML1
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Target
MAML1
(Mastermind-Like 1 (MAML1))
Alternative Name
MAML1 (MAML1 Products )
Synonyms
mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
Background
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. Alias Symbols: MAML1 {ECO:0000312|HGNC:HGNC:13632 Protein Interaction Partner: Su(H), NOTCH1, RBPJ, PBRM1, PHF8, SMARCA4, HDAC9, PIAS1, MAML1, CDK8, EP300, NOTCH3, NOTCH2, CREBBP, NOTCH4, MAML2, MAML3, Protein Size: 1016
Gene ID
9794
NCBI Accession
NP_055572
UniProt
Q92585
Pathways
Notch Signaling , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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