ORC4 antibody (C-Term)

Catalog No. ABIN5517229

Product Details anti-ORC4 Antibody

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IIAMKHLNDI YEEEPFNFQM VYNEFQKFVQ RKAHSVYNFE KPVVMKAFEH

Characteristics: This is a rabbit polyclonal antibody against ORC4. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ORC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ORC4

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Alternative Name: ORC4 (ORC4 Products)

Synonyms: ORC4L antibody, ORC4P antibody, Orc4P antibody, Orc4l antibody, mMmORC4 antibody, CG2917 antibody, DmORC4 antibody, Dmel\\CG2917 antibody, ORC antibody, ORC4 antibody, dmOrc4 antibody, orc4 antibody, rDmORC antibody, orc4l antibody, fc50c03 antibody, wu:fc50c03 antibody, zgc:85772 antibody, ATORC4 antibody, F23H14.9 antibody, F23H14_9 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 antibody, origin recognition complex, subunit 4 antibody, Origin recognition complex subunit 4 antibody, origin recognition complex subunit 4 L homeolog antibody, origin recognition complex subunit Orc4 antibody, ORC4 antibody, Orc4 antibody, orc4.L antibody, orc4 antibody, CNM01830 antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Alias Symbols: ORC4, ORC4L,

Protein Interaction Partner: RRM2B, TCF4, MCM3, MTUS1, MCM10, FBXL8, FBXO6, FBXO25, FBXL5, ORC3, ORC6, UBC, ORC5, ORC2, MLH1, MCM7, KPNA1, CTBP1, CDKN2A, CCND1, APP, XRCC5, XRCC6, CCL2, tat, MCM2, ORC1, MCM6, MCM4, DBF4, RPA2,

Protein Size: 436

Gene ID: 5000

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA