PDE11A antibody (N-Term)

Catalog No. ABIN5517295

Product Details anti-PDE11A Antibody

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WAGGSRGDGN LQRRASQKEL RKSFARSKAI HVNRTYDEQV TSRAQEPLSS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDE11A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A (PDE11A Products)

Synonyms: PPNAD2 antibody, 6330414F14Rik antibody, A630086N24Rik antibody, Gm350 antibody, PDE11A1 antibody, si:ch211-222f23.5 antibody, PDE11A antibody, ppnad2 antibody, Pde11a antibody, phosphodiesterase 11A antibody, phosphodiesterase 11a antibody, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody, PDE11A antibody, Pde11a antibody, pde11a antibody, LOC100470038 antibody

Background: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PPNAD2,

Protein Size: 933

Gene ID: 50940

NCBI Accession: NM_001077196, NP_001070664

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process