Epiregulin antibody (Middle Region)

Catalog No. ABIN5518110

Product Details anti-Epiregulin Antibody

Target: Epiregulin (EREG)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epiregulin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CEHFFLTVHQ PLSKEYVALT VILIILFLIT VVGSTYYFCR WYRNRKSKEP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EREG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Epiregulin

Target: Epiregulin (EREG)

Alternative Name: EREG (EREG Products)

Synonyms: EREG antibody, ER antibody, EPR antibody, proepiregulin antibody, epiregulin antibody, EREG antibody, ereg antibody, Ereg antibody

Background: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

Alias Symbols: ER, Ep, EPR

Protein Size: 169

Gene ID: 2069

NCBI Accession: NM_001432, NP_001423

UniProt: O14944

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation