CDR2 antibody (Middle Region)

Catalog No. ABIN5518746

Product Details anti-CDR2 Antibody

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Binding Specificity: AA 232-2656, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDR2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Cerebellar degeneration-related protein 2(CDR2) detection. Tested with WB in Human,Mouse.

Sequence: ELEQQLGATG AYRARALELE AEVAEMRQML QSEH

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Cerebellar degeneration-related protein 2(CDR2) detection. Tested with WB in Human,Mouse.
Gene Name: cerebellar degeneration related protein 2
Protein Name: Cerebellar degeneration-related protein 2

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CDR2 (232-2656aa ELEQQLGATGAYRARALELEAEVAEMRQMLQSEH), different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Alternative Name: CDR2 (CDR2 Products)

Synonyms: CDR62 antibody, Yo antibody, cdr2 antibody, MGC69206 antibody, CDR2 antibody, AA617262 antibody, RGD1310578 antibody, cerebellar degeneration related protein 2 antibody, cerebellar degeneration related protein 2 L homeolog antibody, cerebellar degeneration-related 2 antibody, cerebellar degeneration-related protein 2 antibody, cerebellar degeneration related protein 2 like antibody, CDR2 antibody, cdr2 antibody, cdr2.L antibody, Cdr2 antibody, CDR2L antibody, LOC101060399 antibody

Background: Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene. By a combination of study of rodent/human somatic cell hybrids and in situ hybridization, this gene is assigned to 16p13.1-p12. The onconeuronal cerebellar degeneration-related antigen Cdr2 is associated with paraneoplastic syndromes. Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor growth by developing tumor immunity, but culminates in cerebellar degeneration when Cdr2-specific immune cells recognize neuronal Cdr2.

Synonyms: AA617262 | CDR 2 | CDR2 | CDR 62 | CDR62 | PCD 17 | PCD17 | Yo | Q01850

Gene ID: 1039

UniProt: Q01850