Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ALDH6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-396 amino acids from the C-terminal region of human ALDH6A1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ALDH6A1
(Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))
MMSADHA antibody, MMSDH antibody, Mmsdh antibody, cb850 antibody, wu:fb03a04 antibody, zgc:92082 antibody, 1110038I05Rik antibody, AI314632 antibody, aldehyde dehydrogenase 6 family member A1 antibody, aldehyde dehydrogenase 6 family, member A1 antibody, aldehyde dehydrogenase 6 family member A1 L homeolog antibody, methylmalonic acid semialdehyde dehydrogenase antibody, methylmalonate-semialdehyde dehydrogenase (CoA acylating) antibody, aldehyde dehydrogenase family 6, subfamily A1 antibody, ALDH6A1 antibody, Aldh6a1 antibody, aldh6a1.L antibody, CCNA_02357 antibody, aldh6a1 antibody, VAA_RS07845 antibody
Background
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.