This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NR5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the Central region of human NR5A2.
NR5A2
Reactivity: Rat, Mouse
WB
Host: Rabbit
Polyclonal
RB51100
unconjugated
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
NR5A2 + LRH1 (NR5A2)
(Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))
xff1rashort antibody, NR5A2 antibody, b1f antibody, b1f2 antibody, cpf antibody, ff1r antibody, ftf antibody, ftz-f1 antibody, ftz-f1beta antibody, hb1f antibody, hb1f-2 antibody, lrh-1 antibody, lrh1 antibody, xff1ra antibody, B1F antibody, B1F2 antibody, CPF antibody, FTF antibody, FTZ-F1 antibody, FTZ-F1beta antibody, LRH-1 antibody, LRH1 antibody, hB1F-2 antibody, xFF1rB antibody, AU020803 antibody, D1Ertd308e antibody, Ftf antibody, UF2-H3B antibody, Lrh-1 antibody, nuclear receptor subfamily 5 group A member 2 S homeolog antibody, nuclear receptor subfamily 5 group A member 2 antibody, nuclear receptor subfamily 5 group A member 2 L homeolog antibody, nuclear receptor subfamily 5, group A, member 2 antibody, nr5a2.S antibody, NR5A2 antibody, nr5a2 antibody, nr5a2.L antibody, Nr5a2 antibody
Background
NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.