Bestrophin 3 antibody (N-Term)

Catalog No. ABIN5530592

Product Details anti-Bestrophin 3 Antibody

Target: Bestrophin 3 (BEST3)

Binding Specificity: AA 40-68, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bestrophin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Bestrophin 3

Target: Bestrophin 3 (BEST3)

Alternative Name: BEST3 (BEST3 Products)

Synonyms: CG12327 antibody, Dmel\\CG12327 antibody, dbest3 antibody, best-3 antibody, BEST3 antibody, VMD2L3 antibody, Vmd2l3 antibody, mBest4 antibody, bestrophin-3 antibody, bestrophin 3 antibody, Bestrophin 3 antibody, BEST3 antibody, Best3 antibody, best3 antibody

Background: BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738], Tsunenari et al., 2003 [PubMed 12907679]).

Molecular Weight: 76 kDa

Gene ID: 144453

UniProt: Q8N1M1