CKM antibody (C-Term)

Catalog No. ABIN5530956

Product Details anti-CKM Antibody

Target: CKM (Creatine Kinase, Muscle (CKM))

Binding Specificity: AA 283-313, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This CKM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the C-terminal region of human CKM.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Alternative Name: CKM (CKM Products)

Synonyms: CKMM antibody, M-CK antibody, Ckmm antibody, MCK antibody, ckmm antibody, m-ck antibody, CKM antibody, CK-M antibody, cb51 antibody, ckm antibody, mck antibody, wu:fa28d05 antibody, ckm3 antibody, wu:fb55e09 antibody, zgc:64204 antibody, zgc:92070 antibody, creatine kinase, M-type antibody, creatine kinase, muscle antibody, creatine kinase, M-type L homeolog antibody, creatine kinase, muscle a antibody, creatine kinase, muscle b antibody, CKM antibody, Ckm antibody, ckm.L antibody, ckm antibody, ckma antibody, ckmb antibody

Background: Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Molecular Weight: 43 kDa

Gene ID: 1158

UniProt: P06732