MCOLN1 antibody (C-Term)

Catalog No. ABIN5531668

Product Details anti-MCOLN1 Antibody

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Binding Specificity: AA 531-560, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCOLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MCOLN1

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Alternative Name: MCOLN1 (MCOLN1 Products)

Synonyms: mcoln1 antibody, mcoln1.1 antibody, zgc:63619 antibody, mln1 antibody, mucolipin-1 antibody, MCOLN1 antibody, MG-2 antibody, ML4 antibody, MLIV antibody, MST080 antibody, TRP-ML1 antibody, TRPM-L1 antibody, TRPML1 antibody, 2210015I05Rik antibody, mucolipidin antibody, mucolipin 1a antibody, mucolipin 1 antibody, mucolipin 1 L homeolog antibody, mcoln1a antibody, MCOLN1 antibody, mcoln1.L antibody, mcoln1 antibody, LOAG_04987 antibody, Mcoln1 antibody

Background: This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV.

Molecular Weight: 65 kDa

Gene ID: 57192

UniProt: Q9GZU1

Pathways: Transition Metal Ion Homeostasis