FBLIM1 antibody (C-Term)

Catalog No. ABIN5532564

Product Details anti-FBLIM1 Antibody

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Binding Specificity: AA 294-323, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBLIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the C-terminal region of human FBLIM1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: FBLIM1 (FBLIM1 Products)

Synonyms: FBLIM1 antibody, CAL antibody, FBLP-1 antibody, FBLP1 antibody, 2410043F08Rik antibody, Cal antibody, Fblp1 antibody, Gt10 antibody, migfilin antibody, migfilin(s) antibody, filamin binding LIM protein 1 antibody, filamin binding LIM protein 1 S homeolog antibody, FBLIM1 antibody, fblim1.S antibody, Fblim1 antibody

Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 41 kDa

Gene ID: 54751

UniProt: Q8WUP2