PCDHB14 antibody (N-Term)

Catalog No. ABIN5532672

Product Details anti-PCDHB14 Antibody

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Binding Specificity: AA 166-193, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB14 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHB14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the N-terminal region of human PCDHB14.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Alternative Name: PCDHB14 (PCDHB14 Products)

Synonyms: PCDH-BETA14 antibody, 2210006M07Rik antibody, Pcdhb17 antibody, PcdhbN antibody, PCDHB14 antibody, protocadherin beta 14 antibody, protocadherin beta-14 antibody, PCDHB14 antibody, Pcdhb14 antibody, LOC487175 antibody, LOC100061546 antibody, LOC100353156 antibody

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Molecular Weight: 88 kDa

Gene ID: 56122

UniProt: Q9Y5E9