LECT1 antibody (C-Term)

Catalog No. ABIN5533235

Product Details anti-LECT1 Antibody

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Binding Specificity: AA 253-281, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LECT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This LECT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the C-terminal region of human LECT1.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Alternative Name: LECT1 (LECT1 Products)

Synonyms: chm1 antibody, chm-i antibody, bricd3 antibody, MGC53801 antibody, MGC82444 antibody, chondromodulin-I antibody, Lect1 antibody, BRICD3 antibody, CHM-I antibody, CHM1 antibody, MYETS1 antibody, Bricd3 antibody, ChM-I antibody, Chm-1 antibody, chondromodulin L homeolog antibody, leukocyte cell derived chemotaxin 1 antibody, chondromodulin antibody, cnmd.L antibody, lect1 antibody, CNMD antibody, cnmd antibody, Cnmd antibody

Background: LECT1 a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This protein is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.

Molecular Weight: 37 kDa

Gene ID: 11061

UniProt: O75829