Indian Hedgehog antibody (N-Term)

Catalog No. ABIN5533581

Product Details anti-Indian Hedgehog Antibody

Target: Indian Hedgehog (IHH)

Binding Specificity: AA 51-80, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human IHH.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: IHH (IHH Products)

Synonyms: BDA1 antibody, HHG2 antibody, X-hh antibody, Xbhh antibody, bhh antibody, bhh-a antibody, IHH antibody, ehh antibody, zgc:113262 antibody, indian hedgehog antibody, Indian hedgehog antibody, indian hedgehog S homeolog antibody, Indian hedgehog homolog b antibody, IHH antibody, Ihh antibody, ihh.S antibody, ihhb antibody

Background: This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.

Molecular Weight: 45 kDa

Gene ID: 3549

UniProt: Q14623

Pathways: Hedgehog Signaling