UBE2L3 antibody (C-Term)

Catalog No. ABIN5533764

Product Details anti-UBE2L3 Antibody

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Binding Specificity: AA 123-153, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2L3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBE2L3

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Alternative Name: UBE2L3 (UBE2L3 Products)

Synonyms: E2-F1 antibody, L-UBC antibody, UBCH7 antibody, UbcM4 antibody, C79827 antibody, Ubce7 antibody, ube2l3 antibody, wu:fc22h11 antibody, zgc:86727 antibody, UBE2L3 antibody, ube2l3l antibody, wu:fb38h03 antibody, ubiquitin conjugating enzyme E2 L3 antibody, ubiquitin-conjugating enzyme E2L 3 antibody, ubiquitin-conjugating enzyme E2L 3a antibody, ubiquitin conjugating enzyme E2 L3 S homeolog antibody, ubiquitin-conjugating enzyme E2L 3b antibody, UBE2L3 antibody, Ube2l3 antibody, ube2l3a antibody, ube2l3.S antibody, ube2l3b antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.

Molecular Weight: 18 kDa

Gene ID: 7332

UniProt: P68036