This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
LETM1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
LETM1
(Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
LETM1 antibody, wu:fc31h08 antibody, wu:fc58h01 antibody, zgc:109969 antibody, letm1 antibody, MGC145623 antibody, leucine zipper and EF-hand containing transmembrane protein 1 antibody, leucine zipper-EF-hand containing transmembrane protein 1 antibody, LETM1 and EF-hand domain-containing protein 1, mitochondrial antibody, LETM1 antibody, letm1 antibody, LOC100346816 antibody, Letm1 antibody
Background
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.