CPSF3L antibody (N-Term)

Catalog No. ABIN5534952

Product Details anti-CPSF3L Antibody

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Binding Specificity: AA 91-119, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: CPSF3L (CPSF3L Products)

Synonyms: DDBDRAFT_0204486 antibody, DDBDRAFT_0234100 antibody, DDB_0204486 antibody, DDB_0234100 antibody, int11 antibody, CPSF73L antibody, INT11 antibody, INTS11 antibody, RC-68 antibody, RC68 antibody, 2410006F12Rik antibody, AU044035 antibody, RGD1306841 antibody, zgc:110671 antibody, CPSF3L antibody, DKFZp469C1432 antibody, cleavage and polyadenylation specific factor 3-like antibody, integrator complex subunit 11 antibody, RNA-metabolising metallo-beta-lactamase domain-containing protein antibody, microRNA 6727 antibody, CPSF3L antibody, INTS11 antibody, ints11 antibody, Ints11 antibody, MIR6727 antibody

Background: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).

Molecular Weight: 68 kDa

Gene ID: 54973

UniProt: Q5TA45