PSMD5 antibody (C-Term)

Catalog No. ABIN5535953

Product Details anti-PSMD5 Antibody

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Binding Specificity: AA 428-457, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSMD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human PSMD5.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PSMD5

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Alternative Name: PSMD5 (PSMD5 Products)

Synonyms: S5B antibody, 1500032A03Rik antibody, AW475925 antibody, S5b antibody, W91691 antibody, mKIAA0072 antibody, proteasome 26S subunit, non-ATPase 5 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 antibody, PSMD5 antibody, Psmd5 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.

Molecular Weight: 56 kDa

Gene ID: 5711

UniProt: Q16401

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway