SEPSECS antibody (C-Term)
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- Target See all SEPSECS Antibodies
- SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))
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Binding Specificity
- AA 444-474, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SEPSECS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SEPSECS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SEPSECS Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- SEPSECS (Sep (O-phosphoserine) tRNA:Sec (Selenocysteine) tRNA Synthase (SEPSECS))
- Alternative Name
- SEPSECS (SEPSECS Products)
- Synonyms
- LP antibody, PCH2D antibody, SLA antibody, SLA/LP antibody, 9130208G10 antibody, AA986712 antibody, D5Ertd135e antibody, SecS antibody, sla/lpl antibody, zgc:55980 antibody, sepsecs antibody, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase antibody, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase L homeolog antibody, SEPSECS antibody, Sepsecs antibody, sepsecs antibody, sepsecs.L antibody
- Target Type
- Antibody
- Background
- The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP, MIM 165060) by seryl-tRNA synthetase (SARS, MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK, MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 [PubMed 19608919]).
- Molecular Weight
- 56 kDa
- Gene ID
- 51091
- UniProt
- Q9HD40
- Pathways
- SARS-CoV-2 Protein Interactome
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