Dnmt2 antibody (N-Term)

Catalog No. ABIN5536035

Product Details anti-Dnmt2 Antibody

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Binding Specificity: AA 201-230, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dnmt2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Mouse Dnmt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the N-terminal region of mouse Dnmt2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Dnmt2

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Alternative Name: Dnmt2 (TRDMT1 Products)

Synonyms: MGC89267 antibody, DMNT2 antibody, DNMT2 antibody, MHSAIIP antibody, PUMET antibody, RNMT1 antibody, Dnmt2 antibody, Rnmt2 antibody, dnmt2 antibody, tRNA aspartic acid methyltransferase 1 antibody, tRNA aspartic acid methyltransferase 1 L homeolog antibody, trdmt1 antibody, TRDMT1 antibody, Trdmt1 antibody, trdmt1.L antibody

Background: MDnmt2 does not appear to be active as a DNA methyltransferase, however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. mDnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.

Molecular Weight: 47 kDa

Gene ID: 13434

UniProt: O55055