GEMIN8 antibody (C-Term)

Catalog No. ABIN5536898

Product Details anti-GEMIN8 Antibody

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Binding Specificity: AA 213-239, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GEMIN8

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Alternative Name: GEMIN8 (GEMIN8 Products)

Synonyms: FAM51A1 antibody, B130034M20Rik antibody, B930082C09Rik antibody, BC023488 antibody, gemin-8 antibody, gem nuclear organelle associated protein 8 antibody, gemin8 antibody, GEMIN8 antibody, Gemin8 antibody

Background: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Molecular Weight: 29 kDa

Gene ID: 54960

UniProt: Q9NWZ8

Pathways: Ribonucleoprotein Complex Subunit Organization