REPS2 antibody (N-Term)

Catalog No. ABIN5537449

Product Details anti-REPS2 Antibody

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Binding Specificity: AA 153-182, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This REPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human REPS2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2 (REPS2 Products)

Synonyms: POB1 antibody, RALBP1 associated Eps domain containing 2 antibody, RALBP1 associated Eps domain containing protein 2 antibody, REPS2 antibody, Reps2 antibody

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 72 kDa

Gene ID: 9185

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway