PDE8B antibody (AA 296-324)
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- Target See all PDE8B Antibodies
- PDE8B (phosphodiesterase 8B (PDE8B))
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Binding Specificity
- AA 296-324
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE8B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PDE8B Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- PDE8B (phosphodiesterase 8B (PDE8B))
- Alternative Name
- PDE8B (PDE8B Products)
- Synonyms
- PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
- Background
- The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 99 kDa
- Gene ID
- 8622
- UniProt
- O95263
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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