ERV3 antibody (C-Term)

Catalog No. ABIN5538651

Product Details anti-ERV3 Antibody

Target: ERV3 (ERV3-1) (Endogenous Retrovirus Group 3, Member 1 (ERV3-1))

Binding Specificity: AA 445-474, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERV3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ERV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ERV3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ERV3

Target: ERV3 (ERV3-1) (Endogenous Retrovirus Group 3, Member 1 (ERV3-1))

Alternative Name: ERV3 (ERV3-1 Products)

Synonyms: ERV-R antibody, ERV3 antibody, ERVR antibody, HERV-R antibody, HERVR antibody, envR antibody, endogenous retrovirus group 3 member 1, envelope antibody, ERV3-1 antibody

Background: The human genome includes many retroelements including the human endogenous retroviruses (HERVs). ERV3, one of the most studied HERVs, is thought to have integrated 30 to 40 million years ago and is present in higher primates with the exception of gorillas. Taken together, the observation of genome conservation, the detection of transcript expression, and the presence of conserved ORFs is circumstantial evidence for a functional role. A functional role is also suggested by the observation that downregulation of ERV3 is reported in choriocarcinoma. [provided by RefSeq].

Molecular Weight: 68 kDa

Gene ID: 2086

UniProt: Q14264