SGEF antibody (AA 378-406)

Catalog No. ABIN5538661

Product Details anti-SGEF Antibody

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Binding Specificity: AA 378-406

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGEF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Alternative Name: SGEF (ARHGEF26 Products)

Synonyms: SGEF antibody, AI303572 antibody, AW491953 antibody, 4631416L12Rik antibody, 8430436L14Rik antibody, RGD1562559 antibody, Sgef antibody, CSGEF antibody, HMFN1864 antibody, Rho guanine nucleotide exchange factor (GEF) 26 antibody, Rho guanine nucleotide exchange factor 26 antibody, Arhgef26 antibody, ARHGEF26 antibody

Background: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Molecular Weight: 97 kDa

Gene ID: 26084

UniProt: Q96DR7