DEAF1 antibody (C-Term)

Catalog No. ABIN5539344

Product Details anti-DEAF1 Antibody

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Binding Specificity: AA 474-502, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEAF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DEAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human DEAF1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DEAF1

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Alternative Name: DEAF1 (DEAF1 Products)

Synonyms: AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody

Background: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm.

Molecular Weight: 59 kDa

Gene ID: 10522

UniProt: O75398

Pathways: Tube Formation