LRP1 antibody (AA 20-155)
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- Target See all LRP1 Antibodies
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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Binding Specificity
- AA 20-155
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LRP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. coli.
- Clone
- 1C8G6
- Isotype
- IgG1
- Top Product
- Discover our top product LRP1 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM:
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- Alternative Name
- LRP1 (LRP1 Products)
- Synonyms
- A2MR antibody, APOER antibody, APR antibody, CD91 antibody, IGFBP3R antibody, LRP antibody, LRP1A antibody, TGFBR5 antibody, A2mr antibody, AI316852 antibody, Lrp antibody, LRP-1 antibody, LDL receptor related protein 1 antibody, prolow-density lipoprotein receptor-related protein 1 antibody, low density lipoprotein receptor-related protein 1 antibody, LRP1 antibody, Lrp1 antibody, LOC100414789 antibody
- Background
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Description: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. ,
Aliases: APR, LRP, A2MR, CD91, APOER, LRP1A, TGFBR5, IGFBP3R
- Molecular Weight
- 504 kDa
- Gene ID
- 4035
- HGNC
- 4035
- Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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