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ERCC3 antibody (AA 242-261)
ERCC3
Reactivity: Human
WB, IP, IHC (p), EIA
Host: Mouse
Monoclonal
3G4
unconjugated
Product Details anti-ERCC3 Antibody
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Target
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ERCC3
(DNA Repair Protein Complementing XP-B Cells (ERCC3))
Binding Specificity
All epitopes for ERCC3 antibodies
AA 242-261
Reactivity
All reactivities for ERCC3 antibodies
Human
Host
All hosts for ERCC3 antibodies
Mouse
Clonality
All clonalities for ERCC3 antibodies
Monoclonal
Conjugate
All conjugates for ERCC3 antibodies
This ERCC3 antibody is un-conjugated
Application
All applications for ERCC3 antibodies
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Protein G Chromatography
Immunogen
Synthetic peptide corresponding to aa242-261 of Human ERCC-3.
Clone
3G4
Isotype
IgG2b
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Discover our top product ERCC3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
0.1 M Tris-HCl, pH 7.5.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at -20 °C for longer.
Target Details for ERCC3
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Target
ERCC3
(DNA Repair Protein Complementing XP-B Cells (ERCC3))
Alternative Name
ERCC3 (ERCC3 Products )
Synonyms
BTF2 antibody, GTF2H antibody, RAD25 antibody, TFIIH antibody, XPB antibody, BTF2 p89 antibody, Ercc-3 antibody, wu:fc25f08 antibody, ERCC excision repair 3, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 3 antibody, excision repair cross-complementation group 3 antibody, ERCC3 antibody, Ercc3 antibody, ercc3 antibody
Background
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kD subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.Synonyms: BTF2-p89, Basic transcription factor 2 89 kDa subunit, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, ERCC-3, TFIIH 89 kDa subunit, TFIIH basal transcription factor complex helicase XPB subunit, XPB, XPBC, Xeroderma pigmentosum group B-complementing protein
Gene ID
2071
NCBI Accession
NP_000113
UniProt
P19447
Pathways
DNA Damage Repair
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