NONO
Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Nmt55/p54nrb is a DNA and RNA binding protein that has been implicated in multiple cellular functions such as regulation of cell division as well as cancer biology. Expression of this protein has been found to be decreased in some human breast tumors, and has been studied as a relevant tumor marker. It has been found that decreased nmt55/p54nrb expression in Estrogen Receptor (ER)-negative human breast tumors or the expression of nmt55/p54nrb variants in ER-positive tumors may indicate the loss of normal growth. It is possible that nmt55/p54nrb acts as a pre-mRNA splicing factor affecting the structure and function of hERalpha.Synonyms: NRB54