PCSK2 antibody (N-Term)
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- Target See all PCSK2 Antibodies
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCSK2 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to NEC 2.
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation
- Immunogen
- KLH conjugated synthetic peptide selected from the N-terminal region of human PCSK2
- Top Product
- Discover our top product PCSK2 Primary Antibody
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- Application Notes
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Alternative Name
- NEC2 (PCSK2 Products)
- Synonyms
- NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody
- Background
- PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.Synonyms: KEX2-like endoprotease 2, Neuroendocrine convertase 2, PCSK2, Prohormone convertase 2, Proprotein convertase 2
- Gene ID
- 5126
- NCBI Accession
- NP_002585
- UniProt
- P16519
- Pathways
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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