Verified
IL12RB1
Reactivity: Human
WB, ELISA
Host: Goat
Polyclonal
unconjugated
Application Notes
Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.3-1 μg/mL. Approx 100 kDa band observed in Human Peripheral BloodMononucleocytes lysates (calculated MW of 73.0 kDa according to NP_005526.1). Theobserved molecular weight corresponds to the glycosylated form. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Functions as an interleukin receptor which binds interleukin 12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin 23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.Synonyms: IL-12 receptor beta, IL-12R-beta-1, IL-12RB1, IL12 receptor beta component, Interleukin-12 receptor beta-1 chain