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GM2A antibody (Internal Region)
GM2A
Reactivity: Human, Mouse, Rat, Rabbit
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-GM2A Antibody
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Target
See all GM2A Antibodies
GM2A
(GM2 Ganglioside Activator (GM2A))
Binding Specificity
All epitopes for GM2A antibodies
AA 164-175, Internal Region
Reactivity
All reactivities for GM2A antibodies
Human, Mouse, Rat, Rabbit
Host
All hosts for GM2A antibodies
Goat
Clonality
All clonalities for GM2A antibodies
Polyclonal
Conjugate
All conjugates for GM2A antibodies
This GM2A antibody is un-conjugated
Application
All applications for GM2A antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-TTGNYRIESV LS
Specificity
This antibody is expected to recognize isoform 1 (NP_000396.2) only.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rabbit. Species reactivity (tested):Human, Rat.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence (aa 164-175) from the internal region of the protein sequence according to NP_000396.2. Genename: GM2A
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for GM2A
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Target
GM2A
(GM2 Ganglioside Activator (GM2A))
Alternative Name
GM2A / SAP3 (GM2A Products )
Synonyms
GM2A antibody, fb96e04 antibody, fb96e10 antibody, wu:fb96e04 antibody, wu:fb96e10 antibody, zgc:110188 antibody, MGC84154 antibody, GM2-AP antibody, SAP-3 antibody, AA408702 antibody, AW215435 antibody, GM2 ganglioside activator antibody, GM2 ganglioside activator L homeolog antibody, GM2 ganglioside activator protein antibody, Gm2a antibody, GM2A antibody, gm2a antibody, gm2a.L antibody
Background
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease.Synonyms: Cerebroside sulfate activator protein, GM2-AP, Ganglioside GM2 activator, Shingolipid activator protein 3
Gene ID
2760
NCBI Accession
NP_000396
UniProt
P17900
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