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SGK1 antibody (C-Term)

SGK1 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783476
  • Target See all SGK1 Antibodies
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    Binding Specificity
    • 20
    • 20
    • 16
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 138
    • 93
    • 75
    • 20
    • 17
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 123
    • 11
    • 4
    • 1
    Rabbit
    Clonality
    • 127
    • 12
    Polyclonal
    Conjugate
    • 66
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    This SGK1 antibody is un-conjugated
    Application
    • 131
    • 57
    • 50
    • 44
    • 40
    • 29
    • 28
    • 22
    • 9
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SGK1 / SGK at C-term. SGK1 antibody is predicted to not cross-react with other SGK protein family members.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the carboxy terminus of human SGK1
    Top Product
    Discover our top product SGK1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    Alternative Name
    SGK1 / SGK (SGK1 Products)
    Synonyms
    SGK antibody, Sgk antibody, sgk-B antibody, sgk2 antibody, cb1083 antibody, sgk antibody, wu:fc20a09 antibody, sgk-A antibody, sgk1 antibody, sgk1-a antibody, sgk1-b antibody, serum/glucocorticoid regulated kinase 1 antibody, Serine/threonine-protein kinase sgk-1 antibody, serum/glucocorticoid regulated kinase 1 S homeolog antibody, serum/glucocorticoid regulated kinase 1 L homeolog antibody, SGK1 antibody, Sgk1 antibody, sgk-1 antibody, sgk1.S antibody, sgk1 antibody, sgk1.L antibody
    Background
    Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development. At least five isoforms of SGK1 are known to exist.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
    Gene ID
    6446
    NCBI Accession
    NP_001137148
    UniProt
    O00141
    Pathways
    MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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