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SGK1 antibody (C-Term)
SGK1
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SGK1 Antibody
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Target
See all SGK1 Antibodies
SGK1
(serum/glucocorticoid Regulated Kinase 1 (SGK1))
Binding Specificity
All epitopes for SGK1 antibodies
C-Term
Reactivity
All reactivities for SGK1 antibodies
Human, Mouse, Rat
Host
All hosts for SGK1 antibodies
Rabbit
Clonality
All clonalities for SGK1 antibodies
Polyclonal
Conjugate
All conjugates for SGK1 antibodies
This SGK1 antibody is un-conjugated
Application
All applications for SGK1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects SGK1 / SGK at C-term. SGK1 antibody is predicted to not cross-react with other SGK protein family members.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
18 amino acid peptide near the carboxy terminus of human SGK1
Top Product
Discover our top product SGK1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for SGK1
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Target
SGK1
(serum/glucocorticoid Regulated Kinase 1 (SGK1))
Alternative Name
SGK1 / SGK (SGK1 Products )
Synonyms
SGK antibody, Sgk antibody, sgk-B antibody, sgk2 antibody, cb1083 antibody, sgk antibody, wu:fc20a09 antibody, sgk-A antibody, sgk1 antibody, sgk1-a antibody, sgk1-b antibody, serum/glucocorticoid regulated kinase 1 antibody, Serine/threonine-protein kinase sgk-1 antibody, serum/glucocorticoid regulated kinase 1 S homeolog antibody, serum/glucocorticoid regulated kinase 1 L homeolog antibody, SGK1 antibody, Sgk1 antibody, sgk-1 antibody, sgk1.S antibody, sgk1 antibody, sgk1.L antibody
Background
Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development. At least five isoforms of SGK1 are known to exist.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
Gene ID
6446
NCBI Accession
NP_001137148
UniProt
O00141
Pathways
MAPK Signaling , Notch Signaling , Steroid Hormone Mediated Signaling Pathway
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