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CTLA4 antibody
CTLA4
Reactivity: Human
FACS, EIA
Host: Mouse
Monoclonal
ANC152-2-8H5
unconjugated
Product Details anti-CTLA4 Antibody
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Target
See all CTLA4 Antibodies
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reactivity
All reactivities for CTLA4 antibodies
Human
Host
All hosts for CTLA4 antibodies
Mouse
Clonality
All clonalities for CTLA4 antibodies
Monoclonal
Conjugate
All conjugates for CTLA4 antibodies
This CTLA4 antibody is un-conjugated
Application
All applications for CTLA4 antibodies
Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Purpose
Mouse monoclonal antibody raised against CTLA4.
Specificity
MAB6927 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory cells in Vitro. It can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model.
Cross-Reactivity
Human
Immunogen
A mixture of stimulated human PBL's and human CTLA4 Ig fusion protein.
Clone
ANC152-2-8H5
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Preservative
Gentamicin sulfate
Precaution of Use
This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 4°C.
Target Details for CTLA4
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Target
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Alternative Name
CTLA4 (CTLA4 Products )
Synonyms
CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody
Background
Full Gene Name: cytotoxic T-lymphocyte-associated protein 4 Synonyms: CD152,CELIAC3,CTLA-4,GSE,IDDM12
Gene ID
1493
Pathways
Cancer Immune Checkpoints
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