HAX1 antibody (Internal Region)

Catalog No. ABIN5596718

Product Details anti-HAX1 Antibody

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Chicken, Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with human, rat, and mouse based on 100% sequence homology. Cross-reactivity with HAX1 from other sources has not been determined.

Purification: Anti-HAX1 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Immunogen:

Immunogen: Anti-HAX1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human HAX1 protein.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-HAX1 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~35 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.78 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Alternative Name: HAX1 (HAX1 Products)

Synonyms: HAX1 antibody, hax1 antibody, HCLSBP1 antibody, HS1BP1 antibody, SCN3 antibody, HAX-1 antibody, Hs1bp1 antibody, HSP1BP-1 antibody, SIG-111 antibody, Silg111 antibody, mHAX-1s antibody, HCLS1 associated protein X-1 antibody, HCLS1 associated X-1 antibody, HAX1 antibody, hax1 antibody, Hax1 antibody

Background:

Synonyms: HS1-associating protein X-1, HCLS1-associated protein X-1, HS1BP1

Background: HAX1 is a ubiquitous protein which promotes cell survival. It is involved in the clathrin-mediated endocytosis pathway and may be involved in the internalization of ABC transporters such as ABCB11. Theoretically it inhibits CASP9 AND CASP3, and may participate in the regulation of intracellular calcium pools. Anti-Hax1 antibody is ideal for researchers interested in Apoptosis, Cancer, Metabolism, Epigenetics and Nuclear Signaling, or Cell Biology research.

Gene Name: HAX1

Pathways: Regulation of Actin Filament Polymerization