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BAK1 antibody (AA 29-187)

BAK1 Reactivity: Human WB, ELISA, IHC, ICC, FACS, Neut Host: Mouse Monoclonal 2H9H7 unconjugated
Catalog No. ABIN5611250
  • Target See all BAK1 Antibodies
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Binding Specificity
    • 19
    • 16
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-187
    Reactivity
    • 77
    • 32
    • 23
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 72
    • 3
    • 2
    • 1
    Mouse
    Clonality
    • 64
    • 14
    Monoclonal
    Conjugate
    • 44
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAK1 antibody is un-conjugated
    Application
    • 67
    • 26
    • 26
    • 18
    • 14
    • 14
    • 13
    • 13
    • 8
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. coli.
    Clone
    2H9H7
    Isotype
    IgG2b
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Alternative Name
    BAK1 (BAK1 Products)
    Synonyms
    BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
    Background

    Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

    Aliases: BAK, CDN1, BCL2L7, BAK-LIKE

    Molecular Weight
    23.4 kDa
    Gene ID
    578
    HGNC
    578
    Pathways
    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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