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BCL2L10 antibody (AA 31-186)

BCL2L10 Reactivity: Human WB, ELISA, IHC, ICC, FACS, Neut Host: Mouse Monoclonal 8A11G12 unconjugated
Catalog No. ABIN5611303
  • Target See all BCL2L10 Antibodies
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Binding Specificity
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-186
    Reactivity
    • 20
    • 16
    • 15
    Human
    Host
    • 32
    • 3
    Mouse
    Clonality
    • 33
    • 2
    Monoclonal
    Conjugate
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL2L10 antibody is un-conjugated
    Application
    • 14
    • 13
    • 13
    • 9
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. coli.
    Clone
    8A11G12
    Isotype
    IgG2a
    Top Product
    Discover our top product BCL2L10 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
    Alternative Name
    BCL2L10 (BCL2L10 Products)
    Synonyms
    BCL-B antibody, Boo antibody, Diva antibody, AA420380 antibody, AU023065 antibody, C85687 antibody, NR-13 antibody, mcl1l antibody, nr13 antibody, sb:cb78 antibody, BCL2 like 10 antibody, Bcl2-like 10 antibody, BCL2-like 10 (apoptosis facilitator) antibody, BCL2L10 antibody, Bcl2l10 antibody, bcl2l10 antibody
    Background

    Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

    Aliases: Boo, Diva, BCL-B, bcl2-L-10

    Molecular Weight
    22 kDa
    Gene ID
    10017
    HGNC
    10017
    Pathways
    Positive Regulation of Endopeptidase Activity
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