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c-MET antibody (C-Term)

MET Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5611438
  • Target See all c-MET (MET) Antibodies
    c-MET (MET) (Met Proto-Oncogene (MET))
    Binding Specificity
    • 43
    • 29
    • 28
    • 21
    • 12
    • 11
    • 8
    • 7
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    • 6
    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 222
    • 124
    • 93
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 194
    • 38
    • 3
    • 2
    Rabbit
    Clonality
    • 190
    • 47
    Polyclonal
    Conjugate
    • 126
    • 19
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This c-MET antibody is un-conjugated
    Application
    • 160
    • 102
    • 43
    • 29
    • 26
    • 19
    • 15
    • 14
    • 12
    • 8
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to Hepatocyte Growth Factor Receptor (MET).
    Purification
    Immunoaffinity Chromatography
    Immunogen
    MET antibody was raised against a synthetic peptide from C-terminus of human c-Met protein Genename: MET
    Top Product
    Discover our top product MET Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0,2 mg/mL
    Buffer
    10 mM PBS/1 % BSA buffer pH 7.4 with 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Target
    c-MET (MET) (Met Proto-Oncogene (MET))
    Alternative Name
    HGF Receptor (MET Products)
    Synonyms
    AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody
    Background
    Met, an HGF Receptor/Met type protein kinase, is a cell-surface proto-oncogene that mediates the biological activities of hepatocyte growth factor. The protein is a disulfide-linked heterodimer comprised of two subunits: a 50 kD extracellular alpha subunit and a membrane-spanning 145 kD beta subunit that binds ligand. Met is an important regulator of cell proliferation and differentiation, organ regeneration, embryogenesis, and tumorogenesis. Constitutive activation mutations of the met gene lead to many cancers, particularly renal papillary carcinoma.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
    Gene ID
    4233
    NCBI Accession
    NP_000236
    UniProt
    P08581
    Pathways
    RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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