IKK alpha antibody (pSer180, pSer181)

Catalog No. ABIN5618070

The Rabbit Polyclonal anti-IKK alpha antibody is suitable to detect IKK alpha in samples from Human. It has been validated for IHC.

Quick Overview for IKK alpha antibody (pSer180, pSer181) (ABIN5618070)

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK alpha antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-IKK alpha Antibody

Binding Specificity: pSer180, pSer181

Specificity: IKK alpha antibody (Ser180/181) detects endogenous levels of IKKa/Ikkb only when phosphorylated at Serine 180/181

Cross-Reactivity (Details): Mouse

Characteristics: Rabbit Polyclonal IKK alpha antibody (Ser180/181)

Purification: IKK alpha antibody was purified by affinity chromatography

Immunogen: IKK alpha antibody was raised in Rabbit using a synthesized phosphopeptide derived from human IKKa/Ikkb around the phosphorylation site of Serine 180/181 (C-T-SP-F-V) as the immunogen.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50-100

Restrictions: For Research Use only

Handling

Buffer: Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 deg C in small aliquots. Avoid repeat freeze/thaw cycles

Target Details for IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Alternative Name: IKK alpha

Pathways: PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins